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11-Beta-Hydroxysteroid Dehydrogenase Type 1 (HSD11B1) Antibody

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  • 产品名称:11-Beta-Hydroxysteroid Dehydrogenase Type 1 (HSD11B1) Antibody
  • 产品型号:abx001363
  • 产品展商:其它品牌
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简单介绍

11-Beta-Hydroxysteroid Dehydrogenase Type 1 (HSD11B1) Antibody

产品描述
HSD11B1 Antibody is a Rabbit Polyclonal antibody against HSD11B1. The protein encoded by this gene is a microsomal enzyme that catalyzes the conversion of the stress hormone cortisol to the inactive metabolite cortisone. In addition, the encoded protein can catalyze the reverse reaction, the conversion of cortisone to cortisol. Too much cortisol can lead to central obesity, and a particular variation in this gene has been associated with obesity and insulin resistance in children. Mutations in this gene and H6PD (hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase)) are the cause of cortisone reductase deficiency. Alternate splicing results in multiple transcript variants encoding the same protein.

Target HSD11B1
Reactivity Human, Mouse
Host Rabbit
Clonality Polyclonal
Tested Applications WB
Recommended dilutions WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user.
Immunogen Recombinant protein of human HSD11B1.
Purification Affinity purified.
Form Liquid
Isotype IgG
Conjugation Unconjugated
Storage Aliquot and store at -20 °C. Avoid repeated freeze/thaw cycles.
Molecular Weight Calculated MW: 32 kDa
Observed MW: 32 kDa
Swiss Prot P28845
GeneID 3290
Gene Symbol HSD11B1
Concentration > 1 mg/ml
Buffer PBS, pH 7.3, 0.02% sodium azide, 50% glycerol.
UNSPSC Code 12352203
Availability Shipped within 5-10 working days.
Note This product is for research use only.
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